Table 2. Univariate and multivariate analysis for overall survival.

Characteristic	Univariate				Multivariate (RCP)				Multivariate (CAP)				Multivariate (modified criteria)
	P	HR	95% CI		P	HR	95% CI		P	HR	95% CI		P	HR	95% CI
Age	0.739	1.089	0.661–1.793		–	–	–		–	–	–		–	–	–
Gender	0.913	1.042	0.496–2.191		–	–	–		–	–	–		–	–	–
Location	0.143	1.395	0.798–2.439		0.929	1.036	0.473–2.271		0.229	1.430	0.798–2.564		0.257	1.401	0.782–2.512
Tumor length	0.106	1.049	0.714–1.542		0.275	1.388	0.771–2.498		0.953	1.012	0.671–1.527		0.692	1.084	0.728–1.615
Differentiation	0.159	0.905	0.582–1.409		0.829	1.046	0.697–1.569		0.738	0.921	0.569–1.492		0.880	0.963	0.594–1.563
Adjuvant therapy	0.105	0.718	0.430–1.198		0.718	0.916	0.568–1.477		0.162	0.685	0.403–1.164		0.267	0.737	0.429–1.264
Operation	0.716	1.073	0.739–1.571
RCP	0.097	1.740	0.905–3.344		0.140	0.669	0.392–1.141
CAP	0.114	1.570	0.898–2.746						0.146	1.517	0.864–2.663
Modified criteria	0.004	2.345	1.307–4.206										0.007	2.253	1.244–4.082

CAP, College of American Pathologists; RCP, Royal College of Pathologists.