Table 2. Comparisons of thyroid hormones of T2DM patients with healthy controls.
| Variables | Controls (n=101) | T2DM without complications (n=202) | T2DM with DN (n=99) | P value |
|---|---|---|---|---|
| Gender (M/F) | 68/33 | 131/71 | 62/37 | >0.05 |
| Age (median), (years) | 56 [33–79] | 57 [37–82] | 63 [37–85] | >0.05 |
| T3 (ìg/L) | 0.97±0.14 | 1.03±0.19 | 0.83±0.13* | <0.01 |
| T4 (ìg/dL) | 87.9±18.1 | 90.4±16.9 | 91.2±17.2 | >0.05 |
| FT3 (ng/L) | 3.03±0.51 | 3.12±0.36 | 2.80±0.44* | <0.01 |
| FT4 (ng/dL) | 9.77±3.01 | 10.01±2.06 | 10.10±3.21 | >0.05 |
| TSH (U/L) | 1.86±0.99 | 1.79±0.62 | 3.08±1.13* | <0.01 |
Data was presented as mean and standard deviation. P value, comparisons of the three groups by one-way ANOVA. *, P<0.001, compared with Controls and T2DM without complications analyzed by SNK–test. T2DM, type 2 diabetes mellitus; T3, triiodothyronine; FT3, free triiodothyronine; T4, total thyroxine; FT4, free thyroxine; TSH, thyroid stimulating hormone; ANOVA, analysis of variance.