Table 1.

Summary of experimental data describing impact of WT versus mutants TRF1HP1α on telomere lengthening and TIF (via 47A or TRF2 depletion)

	Baseline	TRF1HP1α
		WT	V22M	I165A	W174A	NS2A	KRKAAA
Telomere lengthening	+++	+	+	+++	++	+	+
TIF via 47A	+++	+	+	+++	++	++	++
TIF via si-TRF2	+++	+	+	+++	++	+	+

+++ (strong telomere lengthening, high number of TIF), ++ (intermediate phenotype), + (weak telomere lengthening, low number of TIF)