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. 2018 Aug 29;9:718. doi: 10.3389/fneur.2018.00718

Table 1.

Demographics, clinical and MRI data reported as mean along with standard deviation or median (range).

HC (n = 63) CIS (n = 27) RRMS (n = 59) Between group comparison HC and RRMS
Age (y) 35.3 ± 9.9 34.3 ± 7.0 37.5 ± 9.7 t = −1.21 p = 0.23
Gender (F/M) 40/23 19/8 33/26 X2 = 0.72 p = 0.39
Time since onset (y) 2.3 ± 1.4 4.1 ± 2.7
NBV (ml) 1,586.2 ± 72.7 1,599.8 ± 72.0 1,553.6 ± 67.6 t = 2.57 p = 0.01
NGMV (ml) 846.2 ± 57.4 858.3 ± 56.3 823.7 ± 55.0 t = 2.21 p = 0.03
NThalV (ml) 21.5 ± 1.6 21.7 ± 1.1 20.6 ± 1.8 t = 3.01 p = 0.003
NWMV (ml) 740.0 ± 37.3 741.5 ± 38.2 729.9 ± 33.2 t = 1.59 p = 0.11
T2C (n) 3 (0–98) 9 (0–92) 27(1–199) W = 349.5 p = 9.57e-15
T2V (ml) 0.3 ± 0.8 1.2 ± 2.6 4.3 ± 5.3 W = 215 p < 2.2e-16
EDSS median (range) 1.5 (0–3.0) 1.5 (0–3.0)
EDSS Score n n
0 7 10
1 5 13
1.5 7 13
2.0 7 10
2.5 0 7
3.0 1 6
SMSW speed (m/s) 1.8 ± 0.2 1.7 ± 0.3
9HPTdom (s) 17.8 ± 2.3 18.7 ± 3.1
9HPTnondom (s) 19.1 ± 2.6 20.5 ± 6.9
9HPTr (1/mean perf. time) 0.055 ± 0.006 0.053 ± 0.008
SDMT (n) 53 ± 6.8 56.6 ± 11.7

Test statistics from unpaired t-test, Chi-squared or Wilcoxon test as indicated. Values in bold denote significance.