Table 1.
HC (n = 63) | CIS (n = 27) | RRMS (n = 59) | Between group comparison HC and RRMS | ||
---|---|---|---|---|---|
Age (y) | 35.3 ± 9.9 | 34.3 ± 7.0 | 37.5 ± 9.7 | t = −1.21 | p = 0.23 |
Gender (F/M) | 40/23 | 19/8 | 33/26 | X2 = 0.72 | p = 0.39 |
Time since onset (y) | 2.3 ± 1.4 | 4.1 ± 2.7 | |||
NBV (ml) | 1,586.2 ± 72.7 | 1,599.8 ± 72.0 | 1,553.6 ± 67.6 | t = 2.57 | p = 0.01 |
NGMV (ml) | 846.2 ± 57.4 | 858.3 ± 56.3 | 823.7 ± 55.0 | t = 2.21 | p = 0.03 |
NThalV (ml) | 21.5 ± 1.6 | 21.7 ± 1.1 | 20.6 ± 1.8 | t = 3.01 | p = 0.003 |
NWMV (ml) | 740.0 ± 37.3 | 741.5 ± 38.2 | 729.9 ± 33.2 | t = 1.59 | p = 0.11 |
T2C (n) | 3 (0–98) | 9 (0–92) | 27(1–199) | W = 349.5 | p = 9.57e-15 |
T2V (ml) | 0.3 ± 0.8 | 1.2 ± 2.6 | 4.3 ± 5.3 | W = 215 | p < 2.2e-16 |
EDSS median (range) | 1.5 (0–3.0) | 1.5 (0–3.0) | |||
EDSS Score | n | n | |||
0 | 7 | 10 | |||
1 | 5 | 13 | |||
1.5 | 7 | 13 | |||
2.0 | 7 | 10 | |||
2.5 | 0 | 7 | |||
3.0 | 1 | 6 | |||
SMSW speed (m/s) | 1.8 ± 0.2 | 1.7 ± 0.3 | |||
9HPTdom (s) | 17.8 ± 2.3 | 18.7 ± 3.1 | |||
9HPTnondom (s) | 19.1 ± 2.6 | 20.5 ± 6.9 | |||
9HPTr (1/mean perf. time) | 0.055 ± 0.006 | 0.053 ± 0.008 | |||
SDMT (n) | 53 ± 6.8 | 56.6 ± 11.7 |
Test statistics from unpaired t-test, Chi-squared or Wilcoxon test as indicated. Values in bold denote significance.