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. 2018 Jul 16;2(7):786–797. doi: 10.1002/hep4.1179

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© 2018 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Hepatic GJB1 expression tracks with components of NAS activity score and fibrosis. Expression of GJB1, the gene that encodes for connexin 32, from liver biopsies taken from each patient in our NAFLD cohort was determined by real‐time quantitative polymerase chain reaction. Statistical testing for significance was performed using analysis of variance to determine the relationship between hepatic GJB1 and (A) NAS, (B) steatosis, (C) inflammation, (D) ballooning, and (E) fibrosis score. Data represented as mean ± standard deviation. Abbreviation: GJB1, gap junction protein beta 1.