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. 2018 Jul 16;2(7):786–797. doi: 10.1002/hep4.1179

Figure 2.

Figure 2

Connexin 32 deficiency protects against NASH fibrosis. WT and Cx32KO mice were given a CDAHFD for 9 weeks to induce NASH with fibrosis. (A,B) Histologic scoring of liver tissue for inflammation and fibrosis (H&E and trichrome, magnification ×20). (C) Hepatic expression of TGF‐β and COL1A1, key drivers of hepatic fibrosis, in WT and Cx32KO mice. Statistical testing for significance was performed using a Student t test, n = 15 mice per group. Data represented as mean ± standard deviation. Abbreviations: H&E, hematoxylin and eosin; SC, standard chow.