Table 1.

Somatic indel detection performance on the virtual tumor. Tools sorted in descending order of F₁-score

	# of calls	True positive	False positive	False negative	Recall	Precision	FDR	F1-scorea	Max F1-scoreb
Lancet	3891	3586	305	1359	0.72	0.92	0.078	0.81	0.81
Strelka2	4514	3647	867	1298	0.73	0.81	0.192	0.77	0.78
LoFreq	4853	3210	1652	1744	0.64	0.66	0.340	0.65	0.67
MuTect2	4873	2712	2071	2233	0.54	0.56	0.432	0.55	0.58
Strelka	1846	1793	53	3152	0.36	0.97	0.028	0.52	0.71

Bold entries represent the best performing tool on the associated metric

^a F₁-score: harmonic mean of precision and recall, 2 × (precision × recall)/(precision + recall)

^b Maximum F₁-score computed for each combination of precision and recall along the precision/recall curve