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. 2018 Aug 27;1:124. doi: 10.1038/s42003-018-0123-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Steps involved in the heavy atom soaking of crystals growing in the lipid cubic mesophase inside IMISX wells for use in IMISX-EP. a, b Photographic images of the process of cutting open an IMISX well with a scissor, c wicking away excess precipitant solution with a cotton bud from around the crystal-laden mesophase, and d, e adding heavy atom containing precipitant solution by pipette