Figure 2.

NCS observed following MCAO via intraluminal suture insertion. (A–C) Data collected via unilateral EEG recordings from ipsilateral hippocampal and parietal cortical areas. Representative discharges sampled from a mouse following reversible MCAO for 60 min. (D–F) Data collected via bilateral recordings from ipsilateral hippocampal and contralateral cortical areas. Representative discharges sampled from a mouse following permanent MCAO. (G–J) Data collected via bilateral recordings from contralateral hippocampal and ipsilateral cortical areas. Representative discharges sampled from two mice following permanent MCAO (G) or reversible MCAO for 90 min (H). In all illustrated traces, discharge onsets are denoted by filled arrows, and hippocampal discharge termination recognized by suppressed or reduced signals. Baseline signal powers were calculated from 30-s data segments collected during stable behavioral immobility. Pre-discharge signal powers were calculated from 30-s segments collected immediately before the onset of discharges. Discharge signal powers calculated from corresponding data segments. In case of NCS with minimal cortical involvement, cortical signal powers were calculated from data segments that corresponded to concurrently recorded hippocampal discharges. *, p < 0.05, ipsilateral vs. contralateral.