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The Schlafen 12-Serpin B12 pathway regulates enterocytic sucrase-isomaltase expression in HIEC-6 cells. Infection with adenovirus expressing either SLFN12 (AdSLFN12) or SERPB12 (AdSERPB12) increases sucrase-isomaltase (SI) and villin 1 (Vil1) mRNA in HIEC-6 cells vs. adenovirus expressing only the CMV promoter (Adv-CMV) (n=6 pooled from 3 separate experiments, *p<0.05).
