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Rates of immunohistochemical positivity for epidermal growth factor receptor (EGFR) and topoisomerase 2-alpha (TOP2A) appear to be higher in colorectal (CRC) tumors from African Americans (AA) than in Caucasians (CC) patients.
| Immunohistochemical positivity | EGFR |
TOP2A |
||
|---|---|---|---|---|
| AA | CC | AA | CC | |
| Total assayed, n | 89 | 194 | 104 | 250 |
| Positively stained, n | 58 | 102 | 99 | 211 |
| Percentage | 65.2% | 52.6% | 95.2% | 84.4% |
| p-Value‡ | 0.047 | 0.005 | ||
Chi -square test.
