Table 2. . Murine targets and targeting efficacy in mouse models of cancer.
| Nanoparticle | Target | Tumor accumulation |
|---|---|---|
| Gold nanorod (HD = 51, AR = 3) [30] Gold nanorod (HD = 51, AR = 3) |
αvβ3 integrin Untargeted |
15 ppm* (24 h) 45 ppm* (24 h) |
| Gold nanoparticle (155 nm) [27] Gold nanoparticle (85 nm) |
GRPR Untargeted |
0.48% i.d. (4 h) 0.5% i.d.* (4 h) |
| Gold nanoparticle (77.0 nm) [28] Gold nanoparticle (73.2 nm) |
Transferrin receptor Untargeted |
2.5% i.d.* (24 h) 2.5% i.d.* (24 h) |
| Gold nanoparticles (22 nm) [33] Gold nanoparticles (22 nm) |
αvβ3 integrin Untargeted |
0.16% i.d. (72 h) 0.16% i.d. (72 h) |
Studies in the table are limited to gold nanoparticle studies that quantified tumor accumulation via inductively coupled plasma methodologies and contained at least an untargeted control.
*Estimated from bar graphs in the publication.