Table 1.

Classification of adverse drug reaction (ADR) severity for Shenmai injection

Classification of ADR severity
Class I	ADRs are deadly or life-threatening; patients need to be withdrawn from drugs and treated immediately; or ADRs last for more than 1 month.
Class II	Patients have pathologic and physiologic changes and must be withdrawn from drugs and treated; or ADRs last for more than 7 days.
Class III	Patients cannot endure the ADRs and must be given a lower dose or withdrawn from drugs; patients improve after symptomatic treatment.
Class IV	Patients can endure the ADRs, and no lowering of dose or drug withdrawal is necessary. Whether without treatment or through symptomatic treatment, patients improve