Table 1.
Study Sample Demographics and Group Comparison
| Eligible Participants (n = 488) | Group Comparison p value (chi-square or t-test) | Excluded Participants (n = 62) | ||
|---|---|---|---|---|
| Dementia (n = 109) | No Dementia (n = 379) | |||
| Age | n = 109 | n = 379 | n = 62 | |
| -mean age in years (SD) | 79.04 (0.55) | 79.08 (0.59) | 0.54 | 79.09 (0.53) |
| Sex | n = 109 | n = 379 | n = 62 | |
| -% female | 62.4% | 55.9% | 0.23 | 58.1% |
| Living or deceased | n = 109 | n = 379 | n = 62 | |
| -% deceased | 80.7% | 83.3% | 0.08 | 29.0% |
| MMSE score at baseline | n = 109 | n = 379 | n = 60 | |
| -mean score (SD) | 28.10 (1.64) | 28.33 (1.46) | 0.16 | 27.27 (2.67) |
| Height | n = 106 | n = 378 | n = 60 | |
| -Mean height in cm (SD) | 162.11 (9.21) | 163.59 (9.45) | 0.15 | 163.83 (8.53) |
| APOE ɛ4 carrier status | n = 109 | n = 373 | n = 61 | |
| -% carrier APOE ɛ4 | 41.3% | 22.5% | < 0.001 | 27.4% |
| Age 11 IQ (standardised) | n = 101 | n = 339 | n = 53 | |
| -Mean score (SD) | 100.19 (16.18) | 100.22 (14.53) | 0.98 | 98.21 (15.63) |
| FEV1 | n = 106 | n = 378 | n = 60 | |
| -mean rate in litres per second (SD) | 1.95 (0.59) | 1.84 (0.62) | 0.12 | 2.03 (0.68) |
| Grip strength | n = 106 | n = 378 | n = 60 | |
| -mean strength in kilograms (SD) | 25.89 (10.17) | 26.46 (8.87) | 0.57 | 28.18 (8.59) |
| 6 m walk time | n = 105 | n = 377 | n = 59 | |
| -mean time in seconds (SD) | 4.56 (1.53) | 4.84 (2.11) | 0.20 | 4.37 (1.29) |
| Smoking status | n = 108 | n = 379 | n = 62 | |
| -% ever smoker | 42.6% | 61.7% | < 0.001 | 50.0% |
| History of cardiovascular or cerebrovascular disease | n = 104 | n = 373 | n = 58 | |
| -% positive history | 28.9% | 28.2% | 0.89 | 24.2% |
| History of hypertension | n = 108 | n = 375 | n = 61 | |
| -% positive history | 35.2% | 41.9% | 0.21 | 41.0% |
| History of diabetes | n = 109 | n = 379 | n = 62 | |
| -% positive history | 4.6% | 5.8% | 0.62 | 1.6% |
Italicized results demonstrate significance of p<0.05