Table 5.
Authors (year) | Study design | Aetiology | Endpoint | HR |
---|---|---|---|---|
Kudo et al. (2011) [15] | RCT trial | HBV = 20% | TTP | 0.81(0.62–1.07) |
HCV = 60% | ||||
Bai et al. (2013) [46] | Comparative study | HBV = 87.9% | OS | 1.01(0.60–1.71) |
HCV = 4.9% | ||||
Muhammad et al. (2013) [47] | Comparative study | ST:HCV = 69% | OS | 1.04(0.66–1.63) |
DT:HCV = 93% | ||||
Zhao et al. (2013) [41] | Non-comparative study | HBV = 80% | OS | 1.372(0.773–2.437) |
HCV = 5% | ||||
Hu et al. (2014) [14] | Comparative study | ST:B = 82.9% | TTP | 1.01(0.76–1.34) |
T:B = 79.8% | ||||
Yao et al. (2016) [12] | Comparative study | ST:HBV = 84% | OS | 1.228(0.593–2.540) |
T:HBV = 83% | TTP | 0.878(0.494–1.561) |
Abbreviations: HR hazard ratio, OS overall survival, TTP time to progression, RCT randomized controlled trials, ST sorafenib plus TACE, DT DEB –TACE