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. 2018 Sep 4;14:1744806918796763. doi: 10.1177/1744806918796763

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© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Trigeminal nerve injury (TIC) causes persistent mechanical hypersensitivity of the ipsilateral whisker pad. The average 50% mechanical threshold value (grams force) was determined with von Frey fiber stimulation of the ipsilateral (a) and contralateral (b) whisker pads of mice with/without TIC injury (n = 6 per group). The averaged thresholds for naïve (♦) and TIC nerve injury (▪) mice are shown. The ipsilateral and contralateral averages of mechanical threshold values for naïve mice are similar as expected. The contralateral mechanical threshold values of TIC injury mice were similar to naïve controls and did not change from their baseline over time. ***p < 0.001, two-way ANOVA, Tukey’s multiple comparisons test, n = 6 per group.