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. 2018 Sep 4;14:1744806918796763. doi: 10.1177/1744806918796763

Figure 4.

Figure 4.

Relative mRNA levels are shown at days 3, 21, and 28 for Sprr1a (a), Gal (b), and Atf3 (c) in TG from mice with and without TIC, with and without the HDAC inhibitors or vehicle. The gene expression at days 3 and 21 is in contrast to day 28. By 28 days, relative gene expression for Gal and Atf3 in mice with TIC was the same as in naïve mice with or without HDACi’s, while Sprr1a remained elevated 10-fold. SAHA: suberanilohydroxamic acid; TIC: trigeminal nerve injury.