Table 1.
Demographics and clinical information of patients with pulmonary cryptococcosis
| Target68 | Single nodule/mass(n = 27) | Multiple nodules/masses(n = 21) | GGO/GGO with nodules(n = 16) | Miliary nodules(n = 2) | Enlarged mediastinal lymph nodes(n = 2) |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 21 | 15 | 8 | 1 | 1 |
| Female | 6 | 6 | 8 | 1 | 1 |
| Age (years) | |||||
| 0–12 | 0 | 0 | 0 | 1 | 2 |
| 13–20 | 1 | 1 | 1 | 1 | 0 |
| 21–44 | 9 | 6 | 5 | 0 | 0 |
| 45–59 | 14 | 9 | 7 | 0 | 0 |
| ≥60 | 3 | 5 | 3 | 0 | 0 |
| Symptoms | |||||
| None | 17 | 9 | 3 | 0 | 0 |
| Cough | 4 | 5 | 5 | 0 | 0 |
| Fever | 2 | 1 | 2 | 0 | 0 |
| Cough, fever | 2 | 1 | 4 | 2 | 2 |
| Chest pain | 2 | 5 | 2 | 0 | 0 |
| History | |||||
| Diabetes | 1 | 1 | 2 | 0 | 0 |
| Tuberculosis | 1 | 1 | 0 | 0 | 0 |
| Malignant tumor | 1 | 4 | 1 | 1 | 0 |
| Liver cirrhosis | 0 | 1 | 2 | 0 | 0 |
| Glucocorticoid therapy | 2 | 0 | 6 | 0 | 0 |
| Occupational exposure | 1 | 1 | 1 | 1 | 2 |
| CT characteristics | |||||
| Irregular margin | 21 | 17 | 11 | 2 | 2 |
| Spiculated | 18 | 9 | 6 | 0 | 0 |
| Air bronchogram | 14 | 5 | 12 | 0 | 1 |
| Halo sign | 7 | 6 | 9 | 0 | 0 |
| Cavity | 3 | 4 | 1 | 1 | 0 |
| Calcifications | 2 | 2 | 0 | 0 | 0 |
| Primary diagnosis | |||||
| Lung cancer | 17 | 8 | 2 | 0 | 0 |
| Tuberculosis | 1 | 3 | 0 | 1 | 2 |
| Bacterial infection | 3 | 7 | 12 | 1 | 0 |
| Treatment | |||||
| Surgery | 19 | 4 | 1 | 0 | 0 |
| Antifungals | 4 | 14 | 13 | 2 | 2 |
| Surgery combined with antifungals | 4 | 3 | 2 | 0 | 0 |
| Prognosis | |||||
| CNS cryptococcosis | 2 | 0 | 1 | 2 | 0 |
| Significantly small | 4 | 4 | 3 | 1 | 1 |
| No recurrence | 22 | 15 | 11 | 1 | 1 |
| Unknown | 1 | 2 | 2 | 0 | 0 |
GGO, ground glass opacity; CT, computed tomography; CNS, central nervous system