Table 4.
Association between different MTHFR C677T genotypes and the components of MetS.
| No. of cases, n (%) | Adjusted ORa (95% CI) | P value | |
|---|---|---|---|
| Elevated waist circumference | 537 | ||
| CC | 116 (21.60) | 1 | |
| CT | 260 (48.42) | 0.96 (0.45–2.01) | 0.904 |
| TT | 161 (29.98) | 0.60 (0.27–1.32) | 0.204 |
| Elevated BP | 470 | ||
| CC | 77 (16.38) | 1 | |
| CT | 216 (45.96) | 1.61 (1.04–2.50) | 0.034 |
| TT | 177 (37.66) | 3.86 (2.26–6.62) | <0.001 |
| Elevated FPG | 349 | ||
| CC | 52 (14.90) | 1 | |
| CT | 163 (46.70) | 1.76 (1.16–2.67) | 0.008 |
| TT | 134 (38.40) | 2.83 (1.79–4.48) | <0.001 |
| Elevated TG | 478 | ||
| CC | 96 (20.08) | 1 | |
| CT | 219 (45.82) | 0.94 (0.59–1.49) | 0.776 |
| TT | 163 (34.10) | 1.57 (1.03–2.66) | 0.043 |
| Reduced HDL-C | 461 | ||
| CC | 98 (21.26) | 1 | |
| CT | 217 (47.07) | 0.96 (0.60–1.52) | 0.850 |
| TT | 146 (31.67) | 1.07 (0.65–1.77) | 0.781 |
aAdjusted for age, sex, and BMI.
MetS = metabolic syndrome; n (%) = frequency; OR = odds ratio; CI = confidence interval; BP = blood pressure; FPG= fasting plasma glucose; TG = triglycerides; HDL-C = high-density lipoprotein-cholesterol.