Table 3.
Clinical Presentation of Patients With Large Adrenal Tumors Based on Surgical or Conservative Managementa,b
| Variable | Adrenalectomy | Conservative management | P valuec |
|---|---|---|---|
| No. (%) | 457 (65) | 248 (35) | |
| Sex: female, No. (%) | 26 (57) | 111 (45) | .001 |
| Age at diagnosis (y), median (range) | 55 (18-87) | 64 (18-91) | <.001 |
| Mode of discovery, No. (%) | <.001 | ||
| Incidental | 290 (63) | 182 (73) | |
| Hormone excess | 95 (21) | 12 (5) | |
| Cancer staging | 30 (7) | 31 (13) | |
| Otherd | 42 (9) | 23 (9) | |
| Evaluated by endocrinologist: yes, No. (%) | 392 (86) | 170 (69) | <.001 |
| Diagnosis, No. (%) | <.001 | ||
| Adenoma | 118 (55) | 98 (45) | |
| Pheochromocytoma | 155 (98) | 3 (2) | |
| Other malignant | 50 (39) | 77 (61) | |
| Other benign | 57 (49) | 59 (51) | |
| ACC | 77 (88) | 11 (12) | |
| Adrenal mass diameter (cm), median (range) | 5.5 (4-24.4) | 5 (4-15.3) | <.001 |
| Bilateral, No. (%) | 44 (10) | 60 (24) | <.001 |
a
ACC = adrenocortical carcinoma.
b
Range was defined as minimum to maximum value.
c
Indicates statistical significance.
d
Other: mass effect and B symptoms.