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CPNE3 expression and clinical outcome of sorafenib treatment
| Characters | CPNE3 mRNA expression
|
P | |
|---|---|---|---|
| High (n=68) | Low (n=73) | ||
| TTP | 8.0 | 11.0 | 0.0015 |
| 7.2–10.8 months | 10.9–13.1 months | ||
| OS | 10.0 | 14.0 | <0.0001 |
| 8.1–12.1 months | 12.7–15.3 months | ||
| Overall response rate (CR + PR) | 4 (5.9%) | 9 (12.3%) | |
| Disease control rate (CR + PR + SD) | 16 (23.5%) | 32 (43.8%) | |
Abbreviations: TTP, time to progress; OS, overall survival; PR, partial remission; CR, complete remission; SD, stable disease.
