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. 2018 Feb 15;8(2):e018640. doi: 10.1136/bmjopen-2017-018640

Table 4.

Cost-effectiveness of HELP intervention versus enhanced standard care: complete case and imputed data analyses (baseline to 12 months)

Incremental cost QALYs gained
Mean (95% CI) Mean (95% CI)
Base case* £1003 (£837 to £1 168) 0.008 (−0.031 to 0.046)
No adjustment† £861 (£713 to £1 010) −0.037 (−0.100 to 0.027)
Complete case analysis‡ £1022 (£673 to £1 372) 0.018 (−0.021 to 0.058)
Complete case analysis with no adjustment§ £955 (£432 to £1 477) −0.030 (−0.093 to 0.033)

*Data include values imputed using multiple imputation with SEs corrected to account for uncertainty in the imputed values. The QALYs gained are adjusted for age, gender and baseline utility values. The incremental costs are adjusted for age, gender costs in the 6-month period prior to baseline.

†As for the base case analysis except the QALYs gained and the incremental costs are unadjusted.

‡As for the base case analysis except there is no multiple imputation of missing values.

§As for the base case analysis except the QALYs gained and the incremental costs are unadjusted and there is no multiple imputation of missing values.

HELP, Healthy Eating and Lifestyle Programme; QALYs, quality-adjusted life years.