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. 2018 Jun 28;47(4):1131–1140. doi: 10.1093/ije/dyy131

Table 4.

Estimates from various Mendelian randomization methods for the association between education and smoking cessation

Method Beta coefficient 95% CI P-value
IVW MR 0.651 0.352, 0.950 5.54 × 10−5
Weighted median MR 0.600 0.160, 1.040 0.008
Weighted modal MR 0.391 −0.587, 1.369 0.433
MR Egger estimate 0.415 −0.741, 1.571 0.475
MR Egger intercept 0.004 −0.015, 0.022 0.673
Egger SIMEX estimate 0.606 −1.141, 2.353 0.500
Egger SIMEX intercept 0.001 −0.027, 0.029 0.946

Analysis of 41 278 individuals (SNP n = 57 out of a possible 74).