Figure 3.

Mitosis identification process in HPFs extracted from low ODX BCa (top row), intermediate ODX BCa (middle row) and high ODX BCa (bottom row). In the first column, results of the mitosis detection for the original HPF at 40× magnification is depicted. In the second column, the mask after the nuclei detection process is presented. The third column shows a close up for the DNN detection of the mitoses (green circles) depicted in the left most column. Mitosis are rare events: at the selected HPF size the low ODX BCa cases usually does not have mitosis. Meanwhile, intermediate and high ODX HPFs have a slightly larger mitosis count. [Color figure can be viewed at wileyonlinelibrary.com]