Table 2. Allele and genotype frequencies of selected SNPs of PARP1 gene in cases and controls.
| Polymorphisms | Case, n(%) | Control, n(%) | OR (95% CI) | pa | Powerb | |
|---|---|---|---|---|---|---|
| PARP1 | ||||||
| rs3611410 | TT | 82 (17.98) | 93 (23.25) | 1.0 (Reference) |
0.83 |
|
| TC | 97 (21.27) | 91 (22.75) | 1.17 (0.85–1.62) | 0.31 | ||
| CC | 276 (60.52) | 216 (54.0) | 1.30 (0.99–1.71) | 0.05 | ||
| CC+TC | 373 (81.7) | 307 (76.75) | 1.36 (0.97–1.89) | 0.06 | ||
| rs1805414 | TT | 70 (15.3) | 29 (7.25) | 1.0 (Reference) |
0.39 |
|
| TC | 268 (58.49) | 291 (72.0) | 0.80 (0.65–1.00) | 0.05 | ||
| CC | 118 (25.8) | 80 (20.0) | 1.29 (0.94–1.77) | 0.10 | ||
| CC+TC | 386 (84.6) | 371 (92.7) | 0.43 (0.27–0.67) | 0.003 | ||
| rs1805404 | CC | 316 (69.2) | 254 (63.5) | 1.0 (Reference) |
0.05 |
|
| CT | 105 (23.2) | 98 (24.5) | 0.93 (0.69–1.27) | 0.69 | ||
| TT | 35 (7.6) | 48 (12.0) | 0.63 (0.40–1.00) | 0.05 | ||
| TT+CT | 140 (30.7) | 146 (36.5) | 0.77 (0.57–1.02) | 0.07 | ||
OR, odds ratio; CI, confidence interval; OR, CI and pa-value calculated by regression analysis.
Powerb Statistical power analysis using PGA1