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. 2018 Sep 5;13(9):e0199007. doi: 10.1371/journal.pone.0199007

Table 3. Distribution of genotypes and odds ratios (OR) for different histological subtypes of thyroid carcinoma and controls.

Genotypes
PARP1
Controls (n = 400)   Papillary carcinoma *P- value   Follicular *P- value   Medullary *P- value   Anaplastic *P- value
n (n = 351) n carcinoma n carcinoma n (n = 7)
OR (95% CI)   (n = 82) (n = 16)   OR (95% CI)
      OR (95% CI)   OR (95% CI)    
rs1136410
TT 93 64 1.00(Ref) 15 1.00(Ref) 3 1.00(Ref) 4 1.00(Ref)
TC 91 76 0.93(0.66–1.32) 0.71 17 0.88(0.49–1.59) 0.68 4 1.13(0.35–3.59) 0.83 1 0.56(0.06–4.76) 0.60
CC 216 217 1.37(1.03- 1.84) 0.02 48 1.20(0.74–1.94) 0.45 9 1.09(0.40–2.99) 0.85 2 0.340.06–1.77) 0.207
rs1805414
TT 29 57 1.00(Ref) 13 1.00(Ref) 3 1.00(Ref) 1 1.00(Ref)
TC 291 209 0.55(0.40–0.74) 0.0001 47 0.50(0.30–0.82) 0.006 9 0.48(0.17–1.32) 0.15 4 0.49 (0.11–2.26) 0.36
CC 80 91 1.40(0.99–1.97) 0.05 20 1.29(0.73–2.25) 0.37 4 1.33(0.41–4.24) 0.62 2 1.60(0.30–8.39) 0.57
rs1805404        
CC 254 249 1.00(Ref) 55 1.00(Ref) 11 1.00(Ref) 2 1.00(Ref)
CT 98 86 1.00(0.71–1.39) 0.99 18 0.86(0.48–1.53) 0.62 4 1.02(0.32–3.25) 0.96 1 0.51(0.06–4.31) 0.53
TT 48 22 0.49(0.28–0.83) 0.008 7 0.68(0.29–1.57) 0.37 01 0.48(0.06–3.78) 0.49 4 9.77(2.12–45.0) 0.003

OR, odds ratio; CI, confidence interval; OR, CI and *p-value calculated by regression analysis.