Table 4:
Test Characteristics for Previously Defined Cut-Points for Depression and Anxiety Symptom Scales
| Instrument | Cut-Point ≥ |
Sens (95% CI) |
Spec (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
Accuracy (95% CI) |
|---|---|---|---|---|---|---|
| Depression | ||||||
| PHQ-2 | 3 | 0.81 (0.58–0.95) |
0.88 (0.82–0.92) |
0.39 (0.24–0.55) |
0.98 (0.95–0.99) |
0.87 (0.82–0.91) |
| PHQ-9 | 10 | 0.95 (0.76–0.99) |
0.83 (0.77–0.88) |
0.36 (0.23–0.50) |
0.99 (0.97–1.0) |
0.84 (0.79–0.89) |
| HADS-D | 8 | 0.71 (0.48–0.89) |
0.88 (0.83–0.92) |
0.36 (0.22–0.52) |
0.97 (0.94–0.99) |
0.86 (0.81–0.90) |
| HADS-D | 11 | 0.38 (0.18–0.62) |
0.97 (0.94–0.99) |
0.53 (0.27–0.79) |
0.94 (0.90–0.97) |
0.92 (0.88–0.95) |
| PROMIS Depression | T score 60 | 0.67 (0.43–0.85) |
0.90 (0.85–0.93) |
0.38 (0.22–0.55) |
0.97 (0.93–0.99) |
0.88 (0.83–0.91) |
| Kessler-6 | 19 | 0. 43 (0.22–0.66) |
0.97 (0.94–0.99) |
0.56 (0.30–0.80) |
0.95 (0.91–0.97) |
0.92 (0.88–0.95) |
| Anxiety | ||||||
| GAD-7 | 10 | 0.64 (0.35–0.87) |
0.88 (0.83–0.92) |
0.25 (0.12–0.42) |
0.98 (0.94–0.99) |
0.87 (0.82–0.91) |
| OASIS | 8 | 0.71 (0.42–0.92) |
0.82 (0.76–0.87) |
0.20 (0.10–0.33) |
0.98 (0.95–0.99) |
0.81 (0.76–0.86) |
| HADS-A | 8 | 0.77 (0.46–0.95) |
0.65 (0.59–0.72) |
0.11 (0.05–0.20) |
0.98 (0.94–1.00) |
0.66 (0.60–0.72) |
| HADS-A | 11 | 0.61 (0.31–0.86) |
0.86 (0.81–0.90) |
0.20 (0.09–0.36) |
0.98 (0.94–0.99) |
0.85 (0.79–0.89) |
| PROMIS Anxiety | T score 60 | 0.79 (0.49–0.95) |
0.85 (0.80–0.89) |
0.24 (0.13–0.40) |
0.98 (0.96–1.0) |
0.85 (0.80–0.89) |