Table 5:
Test Characteristics for Optimal Cut-Points for Depression and Anxiety Symptom Scales
| Instrument | Cut-Point ≥ |
Sens (95% CI) |
Spec (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
Accuracy (95% CI) |
|---|---|---|---|---|---|---|
| Depression | ||||||
| PHQ-9 | 11 | 0.86 (0.64–0.97) |
0.87 (0.82–0.91) |
0.39 (0.25–0.55) |
0.98 (0.95–0.99) |
0.87 (0.82–0.91) |
| HADS-D | 7 | 0.81 (0.58–0.96) |
0.83 (0.77–0.86) |
0.31 (0.19–0.45) |
0.99 (0.95–0.99) |
0.83 (0.77–0.99) |
| PROMIS Depression | 57.7 (T score) |
0.76 (0.52–0.92) |
0.81 (0.76–0.87) |
0.29 (0.17–0.42) |
0.97 (0.94–0.99) |
0.81 (0.76–0.86) |
| Kessler-6 | 13 | 0.81 (0.58–0.94) |
0.78 (0.72–0.83) |
0.26 (0.16–0.38) |
0.98 (0.94–0.99) |
0.78 (0.73–0.83) |
| Anxiety | ||||||
| GAD-7 | 8 | 0.71 (0.42–0.92) |
0.80 (0.75–0.85) |
0.18 (0.09–0.31) |
0.98 (0.95–0.99) |
0.79 (0.74–0.85) |
| HADS-A | 9 | 0.77 (0.46–0.95) |
0.76 (0.70–0.82) |
0.16 (0.08–0.27) |
0.98 (0.95–1.0) |
0.76 (0.70–0.82) |
| PROMIS Anxiety | 59.4 (T score) |
0.86 (0.57–0.98) |
0.82 (0.77–0.87) |
0.23 (0.12–0.37) |
0.99 (0.96–1.0) |
0.83 (0.77–0.87) |