Fig 7. Paquinimod reduces CD115⁺ Ly6C^hi monocytes and CD115⁺ Ly6C^hi in N-IF mice.

Single cell suspensions from the liver analyzed by flow cytometry, from non-treated N-IF mice (n = 7), N-IF mice treated with Paquinimod for 4 weeks (n = 10) and non-treated 24αβNOD mice (n = 8). (A) Total number and (B) frequency of CD206⁺ cells gated from CD11b⁺ cells; (C) frequency CD206⁺ cells gated from CD11b⁺ F4/80⁺ cells; (D) total number of CD115⁺ cells and (E) frequency of CD115⁺ cells gated from CD11b⁺Ly6C^hi cells. The pooled data from two independent experiments is shown. n.s. = not significant; *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001, unpaired t-test.