Table 2. Demographic and clinical characteristics of participants with and without pruritus.
| Variable | With pruritus | Without pruritus | P value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Participant number | 24 | 61 | ||||||||||
| Visual analogue scale score of pruritus intensity | 4.6 | ( | 2.5, 5.9 | ) | 0.0 | ( | 0, 0 | ) | <0.001 | * | ||
| Age (year) | 57.1 | ± | 13.3 | 54.9 | ± | 11.5 | 0.46 | |||||
| Female | 18 | ( | 75.0% | ) | 37 | ( | 60.7% | ) | 0.21 | |||
| Duration of dialysis (year) | 2.7 | ( | 0.8, 5.9 | ) | 2.1 | ( | 1.1, 3.7 | ) | 0.63 | |||
| Body mass index (kg/m2) | 22.8 | ± | 4.2 | 24.2 | ± | 3.3 | 0.10 | |||||
| Diabetes mellitus | 2 | ( | 8.3% | ) | 21 | ( | 34.4% | ) | 0.02 | * | ||
| Heart failure | 1 | ( | 4.2% | ) | 5 | ( | 8.2% | ) | 0.51 | |||
| Viral hepatitis B | 1 | ( | 4.2% | ) | 7 | ( | 11.5% | ) | 0.30 | |||
| Viral hepatitis C | 2 | ( | 8.3% | ) | 3 | ( | 4.9% | ) | 0.55 | |||
| Daily urine amount (L/day) | 0.19 | ( | 0, 0.33 | ) | 0.40 | ( | 0, 0.70 | ) | 0.17 | |||
| Weekly total Kt/V | 2.11 | ± | 0.27 | 2.07 | ± | 0.31 | 0.60 | |||||
| Weekly renal Kt/V | 0.11 | ( | 0, 0.3 | ) | 0.15 | ( | 0, 0.4 | ) | 0.44 | |||
| Weekly peritoneal Kt/V | 1.91 | ± | 0.30 | 1.81 | ± | 0.28 | 0.12 | |||||
| Total creatinine clearance (L/week/1.73 m2) | 55.2 | ( | 52.9, 63.5 | ) | 58.0 | ( | 49.9, 68.7 | ) | 0.64 | |||
| Renal creatinine clearance (L/week/1.73 m2) | 6.8 | ( | 0, 23.1 | ) | 8.2 | ( | 0, 23.9 | ) | 0.69 | |||
| Peritoneal creatinine clearance (L/week/1.73 m2) | 49.7 | ± | 7.8 | 45.9 | ± | 8.5 | 0.06 | |||||
| Normalized protein nitrogen appearance (g/kg/day) | 1.01 | ( | 0.97, 1.27 | ) | 0.94 | ( | 0.81, 1.13 | ) | 0.05 | * | ||
| Hematocrit (%) | 30.5 | ± | 3.7 | 30.5 | ± | 4.2 | 1.00 | |||||
| Platelets (103/μL) | 219 | ± | 72 | 236 | ± | 69 | 0.32 | |||||
| Albumin (g/dL) | 3.7 | ± | 0.4 | 3.7 | ± | 0.5 | 0.60 | |||||
| Fasting glucose (mg/dL) | 103.5 | ( | 97.0, 118.0 | ) | 100.0 | ( | 90.0, 124.0 | ) | 0.64 | |||
| Total cholesterol (mg/dL) | 195.7 | ± | 58.7 | 185.8 | ± | 38.5 | 0.45 | |||||
| Triglycerides (mg/dL) | 129.0 | ( | 91.0, 227.5 | ) | 113.0 | ( | 74.0, 190.0 | ) | 0.39 | |||
| Creatinine (mg/dL) | 11.0 | ± | 3.8 | 11.9 | ± | 3.2 | 0.25 | |||||
| Uric acid (mg/dL) | 6.7 | ( | 5.5, 7.9 | ) | 6.6 | ( | 6.1, 7.5 | ) | 0.74 | |||
| Alanine transaminase (U/L) | 15.0 | ( | 10.0, 20.0 | ) | 14.0 | ( | 10.0, 19.0 | ) | 0.83 | |||
| Total bilirubin (mg/dL) | 0.2 | ( | 0.2, 0.3 | ) | 0.2 | ( | 0.2, 0.3 | ) | 0.64 | |||
| Ca × P** (mg/dL × mg/dL) | 50.1 | ± | 13.1 | 50.1 | ± | 12.0 | 1.00 | |||||
| Intact parathyroid hormone (pg/mL) | 251.2 | ( | 100.8, 792.7 | ) | 264.1 | ( | 122.5, 462.6 | ) | 0.72 | |||
| High-sensitivity C-reactive protein (mg/L) | 0.3 | ( | 0.1, 0.6 | ) | 0.3 | ( | 0.1, 0.7 | ) | 0.73 | |||
The data are expressed as the mean ± standard deviation for normally distributed continuous variables; as the median (first and third quartiles) for non-normally distributed continuous variables; and as the number (percentage) for categorical variables. P values are calculated using the two-sample t-test, the Wilcoxon rank-sum test, and the χ2 test, respectively.
*P ≤ 0.05.
** Ca × P = Product of albumin-adjusted serum calcium (Ca) and serum phosphorus (P) levels.