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. 2018 Aug 30;11:5269–5278. doi: 10.2147/OTT.S168654

Figure 1.

Figure 1

Knockdown of SOX2OT inhibits NSCLC cell proliferation.

Notes: (A) Relative expression of SOX2OT was examined by qRT-PCR and normalized to GAPDH expression in NSCLC tissues (Tumor) compared to adjacent noncancerous tissues (normal). (B) Relative expression of SOX2OT was examined by qRT-PCR and normalized to GAPDH expression in five NSCLC cell lines compared to BES-2B. (C) Relative expression of SOX2OT was examined by qRT-PCR and normalized to GAPDH expression in A549 and H1299 cells transfected with nontargeting sequences (sh-NC) or short-hairpin RNA against SOX2OT (sh-SOX2OT). Cell proliferation was examined by CCK8 assay in A549 (D) and H1299 (E) cells transfected with sh-NC or sh-SOX2OT. **P<0.01.

Abbreviations: CCK8, cell counting kit-8; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; NSCLC, non-small-cell lung cancer; qRT-PCR, quantitative real-time polymerase chain reaction; SOX2OT, Sox2 overlapping transcript.