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. Author manuscript; available in PMC: 2019 Sep 15.
Published in final edited form as: J Immunol. 2018 Jul 27;201(6):1717–1726. doi: 10.4049/jimmunol.1701241

Figure 1. Role of CBLB during viral infections.

Figure 1.

Naïve Cblb+/+ and Cblb−/− mice were inoculated with LCMV strains to produce acute (Arm), chronic (Clone 13) or persistent (Clone 13, CD4-depleted) infections. (A) Levels of CBLB expression. Values are Mean Florescence Intensity (MFI) ±SD. (B) LCMV-specific CD8+ T cell responses. Values are percent ± SD and MFI of IFNγ (parentheses). (C & D) Epitope-specific CD8+ T cell responses following recombinant DNA (LCMV-NP) vaccination. Percent (C) and IFNγ expression in MFI (D) of CD8+ T cell responses. N=4–5mice/group. *p≤0.05.