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. Author manuscript; available in PMC: 2019 Sep 15.
Published in final edited form as: J Immunol. 2018 Jul 27;201(6):1717–1726. doi: 10.4049/jimmunol.1701241

Figure 6. Ablation of CBLB improves the quality of effector CD8+ T-cells.

Figure 6.

Naïve Cblb+/+ and Cblb−/− mice were vaccinated with either live or heat-killed strain #55 yeast. On day 18, dLNs were harvested to analyze CD8+ T cell responses by flow cytometry. (A) Histograms show transcription factor profile of cytokine-producing CD8+ T cells. (B) Relative proportions of expression of transcription factors in cytokine-producing CD8+ T cells; relative expression was calculated by dividing MFI of each transcription factor by the sum of both MFIs. (C.) Histograms show MFI of cytokines gated on cytokine-positive CD8+ T cells. Values are mean ± SD. N=4–5 mice. *p≤0.05.