Table 1.
Patient | aDLI dose level and day | Pre-aDLI | Post-aDLI |
---|---|---|---|
Acute GvHD Time, Grade (stage) | |||
001 | Level 1, D+35 | None | None |
002 | Level 1, D+35 | None | None |
003 | Level 1, D+35 | None | None |
004 | Level 1, D+42 | None | None |
005 | Level 2, D+42 | D+22 Grade 2 (S2,GI 1, L0) | D+98 Grade 2 (S3,GI 0, L1) |
010 | Level 2, D+34 | None | None |
012 | Level 2, D+35 | None | None |
013 | None given† | None | N/E |
025 | None given§ | None | N/E |
026 | Level 2, D+35 | None | D+52 Grade 4 (S0,GI 4, L4) |
027 | Level 2, D+42 | None | None |
028 || | None Given | N/E | N/E |
030 | Level 2, D+42 | None | None |
033 | Level 2, D+35 | None | D+54 Grade 1 (S2,GI 0, L0) |
035 | Level 2, D+35 | None | None |
015 | Level 3, D+36 | None | D+63 Grade 3 (S3,GI 3, L0) |
016 | Level 3, D+35 | None | D+62 Grade 3 (S2,GI 3, L0) |
018 | Level 3, D+35 | None | None |
023 | Level 3, D+35 | None | D+89 Grade 3 (S0,GI 1, L3) |
Level 1, 103 CD3 T-cells/Kg, Level 2 104 CD3 T-cells/kg, Level 3, 105 CD3 T-cells/kg; S, skin; GI, gastrointestinal; L, liver
died D+32 of bacterial sepsis prior to infusion of aDLI.
Donor not able to donate.
non-engraftment followed by autologous reconstitution