Skip to main content
. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2018 May 31;27(9):1083–1090. doi: 10.1158/1055-9965.EPI-17-1127

Table 3.

Means, 95% Confidence Intervals, and Bias for Spiked Pools with Known Concentrations

Pool Number of Labs N Nicotine, ng/mL 95% CI Target Mean % Bias Range
F 8 48 295.9 286.7 – 305 286 3.462 − 8.5 to 14.8%
G 8 48 699.2 676.2 – 722.4 714 −2.07 − 13.3 to 12.8%
Pool Number of Labs N Cotinine, ng/mL 95% CI Target Mean % Bias Range
F 9 54 610.2 596.1 – 624.3 605 0.860 − 14.5 to 6.0%
G 8 48 1729.3 1673.1 – 1785.5 1729 0.017 − 24.5 to 9.1%
Pool Number of Labs N Hydroxycotinine, ng/mL 95% CI Target Mean % Bias Range
F 7 42 1079.2 1052.9 – 1105.1 1066 1.238 − 11.7 to 9.9%
G 7 42 4046.8 3948.1 – 4145.5 3999 1.195 − 10.2 to 12.7%

One outlier laboratory (#11) was omitted from these calculations