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BBB permeability and distribution of SAR405838 in GBM108-Vector and GBM108-VEGFA
A) Comparison of BBB permeability to Texas Red Dextran in GBM108-Vector and GBM108-VEGFA (scale bar = 1000 um) B) Contrast enhancement on MRI for GBM108-Vector and GBM108-VEGFA C) Comparison of H&E staining in GBM108-Vector and GBM108-VEGFA with MALDI mass spectrometry imaging for Gadavist and SAR405838. Dotted lines on the H&E stained section images delineate GBM108-Vector and GBM108-VEGFA tumors.
