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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Structure. 2018 Jun 14;26(9):1275–1283.e3. doi: 10.1016/j.str.2018.05.005

Figure 3. Rearranged lattice interaction in the M2 mutant.

Figure 3

(A) Structure of WT P4–P6 (grey) fits poorly to the 2Fo-Fc map from the M2 mutant at 1.2σ. (B) Fitting of the M2 mutations to the electron density in (A) reveals the conformational rearrangement in the mutant RNA structure. (C) Stereo view of the J5/5a hinge of WT P4–P6 (molecule B) in green and symmetry-related molecule A in red. (D) The same region in the 3.70 Å resolution M2 structure. Electron density map (2Fo-Fc, 0.8σ) in blue showing the new position of C124.