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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Cancer Res. 2018 Jul 2;78(17):5144–5154. doi: 10.1158/0008-5472.CAN-18-0878

Table 2. Sensitivity and Specificity of Fluorescence for Tumor-Involved Margin Samples.

Sensitivity, specificity, positive predictive value, negative predictive value, and area under the curve of fluorescence signal predictions of tumor-involved margin samples in cohort 2A and cohort 3. Fluorescence signal predictions were compared to predictions made by the primary resecting surgeon.

Cohort 2A Cohort 3 Surgeons
Sensitivity 100% 100% 36%
Specificity 90% 74% 97%
Positive Predictive Value (PPV) 80% 52% 80%
Negative Predictive Value (NPV) 100% 100% 84%
Area Under the Curve (AUC) 0.98 0.97 N/A