Table IV.

The expected effect of direct oral anticoagulants on the most common haemostatic parameters (see text for more details).

Parameter	Expected effect
Antithrombin activity	Overestimation
Protein Ca, protein Sa activity	Overestimation
Coagulation factors	Underestimation
Fibrinogen	Underestimationb
Activated protein C resistance (APC ratio)	Overestimation
Lupus anticoagulants	Difficult result interpretation
Factor XIII	Underestimationb

^aAnticoagulant activity; the chromogenic activity is not affected;

^bin patients on dabigatran.