Table 1.
Patient characteristics
| Characteristics | n = 15 |
|---|---|
| Female, n (%) | 8 (53) |
| Age (years) | 30 (23–34) |
| Body mass index (kg/m2) | 19 (17–22) |
| APACHE II score at entry | 8 (7–9.5) |
| Baseline pulmonary function test | |
| Forced expiratory volume in 1 s (L) | 0.8 (0.6–1.0) |
| Forced expiratory volume in 1 s (% predicted) | 24 (20–26) |
| Forced vital capacity (L) | 1.49 (1.33–1.64) |
| FEV1/FVC ratio (%) | 45 (42–52) |
| Chronic comorbidities | |
| Pancreatic insufficiency, n (%) | 11 (73) |
| Diabetes mellitus, n (%) | 5 (33) |
| Osteoporosis, n (%) | 4 (27) |
| Reason for admission | |
| Cystic fibrosis exacerbation, n (%) | 15 (100) |
| Pulmonary therapy prior to admission | |
| Supplemental oxygen as outpatient, n (%) | 12 (80) |
| Noninvasive ventilation as outpatient, n (%) | 9 (60) |
| Listed for lung transplantation, n (%) | 10 (67) |
| Arterial blood gases a | |
| pH | 7.39 (7.38–7.41) |
| PaCO2 (mmHg) | 53 (49–63) |
| HCO3− (mmol/L) | 34 (31–38) |
| PaO2 (mmHg) | 64 (61–68) |
Continuous variables are expressed as median (interquartile range), and categorical variables are expressed as absolute value (%)
aFor arterial blood gas conditions, please see Additional file 1: Table 1