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. 2018 Sep 6;9(9):178. doi: 10.1038/s41424-018-0044-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Immunohistochemistry was performed with PHB (1:5000) anti-rabbit antibodies. (magnitude ×200) a Localisation of PHB in normal pancreatic tissues, acinar cells and some ductal cells showed very weak cytoplasmic staining. b Very weak positive staining of PHB in cancer cells. c Weak expression of PHB shown by cytoplasmic staining. d Mild expression of PHB shown by plasma membrane and cytoplasm of cancer cells. e Strong expression of PHB shown by plasma membrane and cytoplasm of cancer cells. f PHB was also strong expressed in pancreatic islet cells