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. 2018 Aug 30;9:501. doi: 10.3389/fendo.2018.00501

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Copyright © 2018 Su, Guo, Wang, Wang, Cao and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relevant genes methylated and their expression changes that are involved in the GnRH signal pathway. (A) The potential GnRH signal pathway changes that are caused by DMRs and DEGs. (B) Gene expression analysis of methylated Gs and Gq genes that influence the GnRH pathway. DEG gene expression tests were replicated three times, the data were presented as mean ± SEM and were analyzed by one-way ANOVA test (*P < 0.05).