Figure 2.

ATF3 is involved in NLRP3 inflammasome activation. (A) s100a8 and (B) s100a9 expression was examined at 0, 1, 2, 4, 6, and 12 hpi in bronchoalveolar lavage fluid (BALF) samples. (C) GBP5 expression at the protein and (D) mRNA levels at 0 and 6 hpi. (E) Irf1, Nlrp3, and Il18 mRNA expression at 6 hpi. Data are presented as the mean ± SD of triplicate samples from at least three independent experiments. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, two-way analysis and t-test of variance.