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. 2018 Aug 30;12:187. doi: 10.3389/fnbeh.2018.00187

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Copyright © 2018 Yamamoto, Gris, Sotelo Fonseca, Gharagozloo, Mahmoud, Simard, Houle-Martel, Cloutier, Gris and Gris.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Difference between intermittent and continuously recorded mice by cluster. (A) Nourishment cluster. On days 3, 5, 8, and 10 continuously isolated mice spent more time performing activities in this cluster compared to intermittently isolated mire. (B) Physically demanding cluster. On day 3 continuously isolated mice spent significantly higher percentag of time performing activities in this cluster compared to the intermittenly isolated mice. (C) Habituation cluster. On days 3, 5, 8, and 10 intermittently isolated mice performed activities in this cluster significantly more compared to the continuously isolated mice. (D) Exploratory-like cluster. There was no significant difference between two groups. (E) Sleep-related cluster. Intermittently isolated mice spent significantly higher percentage of time performing activities in this cluster. Two-way ANOVA followed by Tukey HSD was used. n = 8.