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. 2018 Sep 5;8:13238. doi: 10.1038/s41598-018-31698-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cholesterol excretion pathways remain unaffected by dietary sc- and lc-inulin. (A) Biliary cholesterol secretion; (B) total fecal neutral sterol (NS) excretion; (C) intestinal fractional cholesterol absorption; (D) trans-intestinal cholesterol efflux (TICE). At day 14 bile cannulation was performed for continuous collection of bile. Feces were collected over 72 h and analyzed for NS as detailed in methods. Fractional cholesterol absorption was measured using the plasma dual isotope method. Data are presented as box plots showing median (interquartile range) and min/max; at least n = 6 for each group.