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. 2018 Aug 30;9:1962. doi: 10.3389/fimmu.2018.01962

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Copyright © 2018 Simon, Wu, Cruard, Vignard, Fortun, Khammari, Dreno, Lang, Rulli and Labarriere.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TRAJ and TRBJ usage of specific-T cell populations. (A) Number of TRAV-12-2 clonotypes using individual TRAJ in the control sample and Melan-A specific T cell repertoire. (B) Number of TRAV-19 clonotypes using individual TRAJ in the control sample and MELOE-1 specific T cell repertoire. Black histograms illustrate TRAJ chains preferentially used in each T cell repertoire, and the same chains are marked with an asterisk in the control sample. (C) Heatmaps of TRBV-TRBJ combination usage for Melan-A (upper panel) and MELOE-1 (lower panel)-specific T cell repertoires. Numbers of clonotypes using a given combination are indicated in the corresponding square.