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. 2018 Jul 30;41(8):742–752. doi: 10.14348/molcells.2018.0201

Fig. 1. REV-ERBα deficiency exacerbates motor impairment induced by 6-hydroxydoapmine (6-OHDA).

Fig. 1

(A) Cylinder tests were performed 3 days, 1 week, and 2 weeks after vehicle (VEH) or 6-OHDA injection in wild type (WT) and Rev-erbα knockout (RKO) mice. Data are presented as mean ± standard error. N = 5–7 per group. Two-way analysis of variance was followed by Tukey’s post-hoc test; ###p < 0.001 versus VEH-injected group; *p < 0.05, ***p < 0.001 versus WT mice; †††p < 0.001 versus 3 days post-lesion. (B) Rotarod tests were performed 3 days, 1 week, and 2 weeks after the VEH or 6-OHDA injection in WT and RKO mice. Data are presented as mean ± standard error. N = 5–7 per group. Two-way analysis of variance was followed by Tukey’s post-hoc test; ##p < 0.01, ###p < 0.001 versus VEH-injected group; **p < 0.01 versus WT mice.