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. 2018 Sep 5;8:13267. doi: 10.1038/s41598-018-31596-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Time course of differential gene expression in hypergravity. Human myelomonocytic U937 cells were exposed to 20 s and 75 s of hypergravity. The numbers of annotated transcripts grouped according to their regulation after the two exposure times are shown. Continuous response means that annotated transcript are either up- or down-regulated at both time points. Adaption is either disappearance of the hypergravity induced effect or regulation in the opposite direction after 75 s. Late response is a regulation that only appears after 75 s. Most transcripts did not respond to hypergravity at both time points.