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. 2018 Jul 26;109(9):2632–2640. doi: 10.1111/cas.13717

Figure 2.

Figure 2

Formation of tetraploid cells. A, Mitotic slippage is a phenomenon in which mitotic cells enter into the next cell cycle without chromosome segregation and cell division, which can be caused by prolonged mitotic arrest due to defective kinetochore‐microtubule attachments. B, Cytokinetic failure occurs when cleavage furrow formation or resolution is disturbed, which can be caused by lagging chromosomes