Table 3.
Utility values for CINV outcomes
| Health state outcomes by phase | 5‐d QALY | |||
|---|---|---|---|---|
| Acute phase (day 1) | Delayed phase (days 2‐5) | Base case | Lower bound | Upper bound |
| CP | CP | 0.0123 | 0.0096 | 0.0137 |
| CRB | 0.0101 | 0.0073 | 0.0126 | |
| IR | 0.0047 | 0.0035 | 0.0056 | |
| CRB | CP | 0.0118 | 0.0090 | 0.0134 |
| CRB | 0.0096 | 0.0067 | 0.0123 | |
| IR | 0.0041 | 0.0029 | 0.0053 | |
| IR | CP | 0.0104 | 0.0081 | 0.0117 |
| CRB | 0.0082 | 0.0058 | 0.0106 | |
| IR | 0.0027 | 0.0019 | 0.0036 | |
5‐d QALY = ([utility value (acute phase) × 1 d] + [utility value (delayed phase) × 4 d])/365 d. The utility values of 0.9, 0.7 and 0.2 were assigned to CP, CRB, and IR, respectively.
CINV, chemotherapy‐induced nausea and vomiting; CP, complete protection; CRB, complete response at best; IR, incomplete response; QALY, quality‐adjusted life years.